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PROTEOBACTERIA >> Epsilon >> Helicobacter >> Helicobacter pylori
HELICOBACTER PYLORI
| Class: | Epsilon Proteobacteria |
| Genus: | Helicobacter |
| Species: | Helicobacter pylori |
| Description: | Helicobacter pylori was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. |
| Synonyms: | |
| Source: | Found enterohepatically (in the liver). |
| Pathogenicity: | |
| Genbank: | NC_000915.1 [Genome] [Nucleotide] |
| Size (Mb): | 1.67 |
| GC %: | 38.9 |
| Genes: | |
| CDS Number: | |
| Reference: | Amieva, Manuel; Peek, Richard M. (2016). "Pathobiology of Helicobacter pylori “Induced Gastric Cancer". Gastroenterology. 150 (1): 64-78. ISSN 0016-5085. PMC 4691563. PMID 26385073. doi:10.1053/j.gastro.2015.09.004. |
| Biochemical Tests: |