>Aeropyrum pernix K1, gi|118430835:1079589-1080773-citrate synthase 
MSQQPECRVEGNYIIVPKGLVNVIVDETRISGVDPKGEATIYRGYTIEDIGEHASFYEAAHLILFGRLPC
DEELKEIKSKIDKYRGQIPEKLFDAMKHVPVTHPMYYGIYGTALLGQYYAPEWRFDEDFLYDHALRLTAQ
LPVIFTTGWNLAHHGTFLRPDPSKDHAWDVLRMIVMREPSDIEARAFESTLVLYMDHGFNASTFTTRVIG
STLSDLYSAVAGGIAALKGPLHGGANEKAMEMFLDAMKKAEEKGVPLYDYIEEYIKEKLARKEKIMGFGH
RIYKLHDPRTDVAAKFVAKLKDGEFWMKVLKKAEEVMWREKKIPANIDLYTAVLYYQLGIPIPMYTPIFA
MGRVVGWSAHYIEQVLNNKLIRPTEKYVGPTGLKYQPIEERCRK*
>Archaeoglobus fulgidus DSM 4304, gi|6626247:1197731-1198849-Citrate Synthase
SPFRQRDELLLLLPHILRSWPYKPVVLVLLYDVGSPA*NPAHSEDVDEEVVGNAEVGVNACGVEVNVWKE
LLVLVSSLGDGLADFEPLR*AFSSKSFSQIPQQLRPWVHNSSVNPVPESHYPLSSLYFSFHVLLSPSWRC
NLPKHPHDLLRRSSMQRPHQRSSCGNNAGVDVCKS*RCNPRRKG*GI*LVLRVKN*IHVQRSLSSFGWFL
PVKHVQKVCSMAEFKSWRNYVPSRPDSVIVSHYCGKLGNQVLCLVESFLPRPYSYLLVKAAEVACCSSEH
DHGVRVWRQMSEETYDLRW*LPPLSKLYFEVLKLVFLRQLSVKQKVSHLLVACLSRKVTDVVTPVLKNCP
PVFKGNPRNRGFAGNHIFQSVLH
>Pyrobaculum aerophilum str. IM2, gi|18311643:989250-990479-citrate synthase
LSLFKRDVL*IVGANIASPRPEYPVVLPVLQDVRNPAHYSRHGEYWGEVLIRYPHVIKRYSGPEVDVWV*
LPLLEIGVAQYFLLYGAGDCKQVLGIAEFGYIIS*KLFKYLGPWIICLIYAVADAH*LWPAWLSRRLYYL
LGLSRSAYFEVVPNGHFISPAVQRAFKCGYCSGY*GVEVAQRRRNDVGSESAGGDLVICVEY*VEIYPPR
GKGIWLSAEHHVEKVRRVSQIVSRPYYL*STRESVVIRHYCRHFGHKLLGYSIRKLLLLGFIPAY**RLY
*FLVVFIVRALRRHSRL*RKHGMGLGEVSNYLNCRRVELSVFFHSINVIFKLPLRRQPPI*NEVRDLFIS
REPGQLFYPIPSVPKNALLAVYIAY*CAFYQNVF*TVNNGTTGRLKNFTRSFYLNSLFTH
>Sulfolobus-solfataricus P2, gi|15896971:2356652-2357785-methylcitrate synthase 
MSVVSKGLENVIIKVTNLTFIDGEKGILRYRGYNIEDLVNYGSYEETIYLMLYGKLPTKKELNDLKAKLN
EEYEVPQEVLDTIYLMPKEADAIGLLEVGTAALASIDKNFKWKENDKEKAISIIAKMATLVANVYRRKEG
NKPRIPEPSDSFAKSFLLASFAREPTTDEINAMDKALILYTDHEVPASTTAALVAASTLSDMYSSLTAAL
AALKGPLHGGAAEEAFKQFIEIGDPNRVQNWFNDKVVNQKNRLMGFGHRVYKTYDPRAKIFKKLALTLIE
RNADARRYFEIAQKLEELGIKQFSSKGIYPNTDFYSGIVFYALGFPVYMFTALFALSRTLGWLAHIIEYV
EEQHRLIRPRALYVGPEYQEYVSIDKR*
>Sulfolobus-tokodaii str. 7, gi|24473558:572987-574108-citrate synthase
MEIKKGLEDVYVKETEITYIDGELGRLYYRGYSIYDLAEFSNFEEVSYLILYGKLPNREELNWFQEKLRE
ERYLPDFIIKFLREVRKDAQPMDILRTAVSLLGIEDSKNDERTDIKGIKLISKFPTIVANYARLRKGLDI
IEPDPKLSHSENFLYMLYGDRPNEIKSKAMDVTLILHIDHEMNASTFASLVVASTFSDLYSSIVAGISAL
KGPLHGGANYEALKMFKEIGSPEKVNDYILNRLSNKQRIMGFGHRVYKTYDPRARILKQYAKLLAEKEGG
EIYTLYQIAEKVEEIGIKYLGPKGIYPNVDFFSSIVFYSLGFEPDFFPAVFASARVVGWVAHIMEYIKDN
KIIRPKAYYKGEIGKKYIPIDSR*
>Bacillus subtilis subsp. subtilis str. 168, gi|50812173:1020365-1021465-citrate synthase 
MVHYGLKGITCVETSISHIDGEKGRLIYRGHHAKDIALNHSFEEAAYLILFGKLPSTEELQVFKDKLAAE
RNLPEHIERLIQSLPNNMDDMSVVRTVVSALGENTYTFHPKTEEAIRLIAITPSIIAYRKRWTRGEQAIA
PSSQYGHVENYYYMLTGEQPSEAKKKALETYMILATEHGMNASTFSARVTLSTESDLVSAVTAALGTMKG
PLHGGAPSAVTKMLEDIGEKEHAEAYLKEKLEKGERLMGFGHRVYKTKDPRAEALRQKAEEVAGNDRDLD
LALHVEAEAIRLLEIYKPGRKLYTNVEFYAAAVMRAIDFDDELFTPTFSASRMVGWCAHVLEQAENNMIF
RPSAQYTGAIPEEVLS*
>Deinococcus radiodurans R1 chromosome 1, gi|15805042:772144-773379-citrate synthase
VCPARSHLFVTPAGTFDRPFFAPWKKGRCYPLLTMSNIAKGLEGVLFTESKLTFINGSEGILTHLGIPIQ
EWAEKSTFEELSLALLDAKLPTAEELAKFDAELKANRAIPDQLVGIIRDMPKGVHPMQALRTAVSYLGLL
DPQAEDITPEARRAISTRMIAQFSTIIAAINRAQEGQDIVAPRADLTHAGNFLYMLTGNEPTPEQARLFD
IALVLHADHGMNASTFTAIATSSTLSDMYSCMVSAIGALKGPLHGGANEAVMTMLDEIGTVDKAEAYITG
KLDNKEKIMGVGHRVYKYFDPRSRVLRDYAEHVANKEGKSNYYQILEAIEKIIVDRMGAKGIYPNVDFYS
GTVYSDLGIKKEYFTPIFALARISGWCASVIEYSQDNRLLRPDAEYTGARDQHYVDIKDRQ*
>Escherichia coli str. K-12 substr. MG1655, gi|49175990:752408-753691-citrate synthase
LTLDIAFKVAFFISCIQLTRTGNLHTVTVHFAPVGDPANGTCHCENDGEHGRRNTHRFQDDTRVEIDVRV
QFLLDKVRVVQRDVFQLHSHFQQVILRAQLFQHFMAGFTHYGGARVVIFVHAVTEAHQAERIIFVFRTTN
KFRNVFNGADFFQHFQRRFVSTAVRRSPQ*SNTCCDTGKRVRTRRASGTHGGGRGVLFMVSVQDQNTVHS
TFQNRINFIRFARRGEHHIQEVTGVGEIVARVNKWLTNGILVTHRGHGRHFRQQAERGNFTVTRIVNIQR
VVIERRQRAGNTTHDCHWMRVATESMEQTGNLLVDHGMTGHRSFKFVILFLSRFFTIQQDVTNFQVVRIG
RQLIDRETAVQQNTFITINKSNFRFAGCG*SEAWVKGEHTF*TESTDINNILTQRAFQHIQFNSCIPVEG
EFCFCISH
>Halobacterium sp. NRC-1, gi|15789340:1544781-1545911-citrate synthase
LPLVEGRAVAVLGTHVSRARSDEAVVVVLFEDVADPAADAGHGEDRRVDVDGDPHLVVRRRRVEINVRRE
ALLISHVILDGDAHLVPFGVAGGRTELLAALAEDVRPGVFDVVDAVAEPHHALAVRQGVLDPGQRVLVAV
VDLLEHPHDVGVRAAVEAARERADRGRDRGVDVRQRACRDHPGERGRVQAVVGVQHQRLVEDVREHVVGR
LAVQHVQEVRGVAEVVAGCDHVVAVPEARERRDDGGEFRGDAFP*LAGVVGIRAAGGVVVRGQRRGGGSE
RGHRVGVGGREVLDEREDVVVDLAVARHVRPEGVEFGSRREVAVPKQVQHFLVAGGAREVLDGVSAVHEL
AGVAVDEAQVGFGHEHVFEPLLEFVGH
>Yersinia pestis CO92, gi|16120353:1251398-1252678-citrate synthase
LFFQLALEITFCIASIKLARTGNLDAVIMHFVPVSNPTDGSGNGEYHRKH*RWNPHGFQDNT*IEVHVWI
QFFLNEVRIVQCDVFQLHRHF*QAVIQLQLF*HFMTGFTHDGGTRVIVFIDTVTKTHQTE*VILIFRAAD
KFRDMLNSFNLFQHLQAGFIGTTVRRAPQGCDPRGDTGKRVSARRAGSTDGRC*RVLFVICVQDENTIHS
AFQYWVNFIFLTWRREHHV*EVTRVGQIVTWINKRLTQ*IFITHRCDSRHFRQQTEGGNFTMALVINIQS
IMVEGG*RTSNPT*HGHRM*IAAETMEQTGDLLVDHGMSGHCGFERFVLFWRRCFAVQQNVTNFQISRIF
CQLGNREATVQQNTLITINIGDF*FAGCGRGKTGVKGKITFRT*GADVDHVSAEGWG*DTQFDRSFA*IQ
RRFFVSH
>Colwellia psychrerythraea 34H, gi|71277742:2314249-2315535-citrate synthase 
LSFI*WYEFTVNFTRVFLTRTTDFLTRLRQHFIPVSNPTYRSRHSKNHGKHT*RNANCF*DDT*VKINIR
VKFFLNKVWVFKSNFF*CHSDIK*RIADTKFIQYFMTSFTHDCCTRIEVFINTMTKAH*TEWVIFIFSFS
YIFSNVF*ATNLFKHSKTCFISAAMCWAP*RCNTSCYTSIRVSTRRTG*TNSRS*SILFMISM*SKDSVH
SISYGRAYYIFFSRY*EHHVKEVFSVRKLIAWVNKWLTNTIFISHCSDSRHFSNQSMSTTFTLCRVSDI*
VTVIER*HCTNNTTKHSHWMCIR*ETMEEMN*LLMYHGMCSDD*LKFFIL*LSWRIAIQ*DITNFKVISL
FS*AINRVTAVL*NTFAAINVGNR*FTRTRC*KARIVGEIAMAT*SSNINYVSTCSTF*NWKFTNFFAIN
TQSGF*FSH
>Desulfotalea psychrophila LSv54, gi|51243852:426190-427476-citrate synthase
LPLFKGDKGSLLPPRIDLTWPGNTEVLVMQFPPICYPAGHSTNGKHHRVHLRRNSYCPEKNAAIEIDIRV
EFTTDKVLIFQGFLLKLQGNIKQRIGFVQLCKYLINPLLEDAGPGIKIFIDPMAKAHQFVIVTFILCPVD
IIVNLPARGHNLFQHLYHGCIGTTMQGSPKGTYP*GDGTKQVRPGTGHCSHR*GRAVLLMIGMEYQEKCQ
SPFDSWTGDIFLKGLGKHHMQKICTVSEMGVWLIKGFADRHPIGPGCYGSNLGQEEGGSSIKAMPL*VYL
QNTGVETGDQVKHCRENRHGRRRFGKSGKVVIEACVQWRMFCQGPAKPVQGFCIGKFTIDNQRACLHKTC
PLRYLLNRVATITQDSSLTINICDIREAGTSTAKAWIHGDIARFST*RLNINTPLILRSTGNIKFITCTA
NSQGCFFTH
>Leptospira interrogans str. Fiocruz L1-130, gi|45655914:3432810-3434099-citrate synthase 
MAEVAILKIDGKEYELPIVIGTEKEKAIDISKLRQQTGYVTLDNGYLNTGACTSAVTFLDGELGILRYRG
IPIEQLAENSTFTEVAYLLIYGKIPSDSELKKWNDELTMHTLIHEDLKRLYNGFPKDGHPMAIMSSMIGS
LSTYYQDSYDPENAEHRHISMIRLLAKFPTIAAFAYKKSIGQPTIHPLNSLDYCANFMNMMFSVPSEDYK
IDPEIVKALNLLLILHADHEQNCSTSTVRLVGSSLANLYGAISAGICALWGPRHGGANQEVLEMLQEIQA
SGLPVKKIVEKAKDKNDSFRLSGFGHRVYKNFDPRAKIIKKACDSVLKRLGVQDSLLDIAKELEETALHD
PYFVERKLYPNVDFYSGIIYRALGIPVNMFTVMFAMGRLPGWIAQWKEMIESPDMKIGRPRQIYTGSTET
SYKEAKKKA*
>Photobacterium profundum SS9 chromosome 1, gi|54307237:1159467-1160756-citrate synthase 
LLSFMKRFKFAL*FTSVKLTRTTDAIIRVTVHFAPVCNPTNSPRHGENNRKH*NWNTNSFQD*T*VEIDI
RVQFLVNKVRVRKCDTFQFHCYIKQWVLDIKLF*YFMTCFTHYCRTWVIVFVNAVTKAHKTERVIFVFCT
FYIFCNFINAANFF*HFQAGFICPAMCRSPK*RNTSCNTCKRVSA*RAS*TYSRC*SILFVIGMQGEDLI
HCTRNNWANIILFTRSRKHHMQEVFCII*IVAREDEWLSN*VFVTH*SKCRHF**QTECRDFTVAIIVDI
*RIMVKRCKCSNHTTHNCHRVSISTETVEEASNLFMNHCVTSHCSTEKFVLSSGWHFTI*QYVTYF*VVS
VIG*LVDRVATV*QDTFVAINVSNLRFT*CCG*KTRIKCKVTASAKFTHINYIWPLRAPKNW*FDWGFPF
NMKSRFLIRH
>Psychrobacter arcticus 273-4, gi|71064581:111902-113182-citrate synthase
LFTIFNFNKIAMRFTSI*LTWTTDFERCAVHLKPMADPTRGTSQ*EDDSKH*RWDSDGF*DNARVKVNVW
IQVTLNEERVF*SNFLKRHCKLKLRIIDTQCA*YFITRFFHDLCTWVKVFINTMTKAHQFHFTALHFFHE
LRHVFYRTDFIEHLKYRFVGATM*WTPQCCDTSSDTSVRVCASRAS*TYGRR*CVLLMVSMQGKDFVHGA
SDNVIGFIINISRRCKHHV*EVFSIIEIITWVHERFAF*VLITHSGKRWHFSDKTNRCNLTMFFVANI*I
FMIKR**STNDTNHNRHWMRVTAEAFKELTQLIMNTHMLTDFFIEICFLLSVRQVTMNQCISHF*IFCIV
C*LVDRVAAMQ*FAFTTINEGDF*FDRSGCHKAWIIGPVASFLESSNINN*RS*SAFSNRKLVILTIYGQ
CGLIISH
>Picrophilus torridus DSM 9790, gi|48477072:907818-908939-citrate synthase
MSISLGLEDVFIKYTSLTSIDGEKGELRYRGYDIKDLVEHCSFEEVAYLMFYGELPKRDELEHFKSNVMK
NYKIPENVKNIIKNMPRDGDALAIMEAAFAALSTEEYTWEKERDREKAAEIMGRALGIVSAVFRYRDGRE
IKDPENKGYAEAFLNACFDSGIDEDKIKAMNAALILYIDHEVPASTTAALVASSTLSDMYSCVTAAIAAL
KGPLHGGAAEAAYKQFLAIKSPENVDSWFNENILNNKKRLMGFGHRVYKTYDPRMLIFKELARKNAKTDE
QKKILELAERLEALGVKNFGQKKIFPNTDYYSGIVFNEIGFPLYMFTTLFALSRVVGWVAHISEYVESEE
RLIRPRAIYIGPEKRDVVPIDKR*
>Thermobifida fusca YX, gi|72160406:276595-277701-citrate synthase 2
LDALGEGFVGAFDALDVAHSGADVAGAGPDQAAGALLLQDVRGPSRGAGAGEHGREHRRRDLREVQHHRG
PVLHVGGEHPVGLAGLQFFQGGLLQGAGDFEAGGVQFLGGTAQDPGPGVFCAVDTVTEAHQALAPVQGLG
DVLARVTEAFRLVEHVQHAGGCAAVQRTGHGTHGSGEGGGHVGTSGGDDPGSERGGVHAVFGSGRPVGVN
GLDVEGVRFATQLDHEPFDDGLTFVDPALRNLGLVPAGGLGDDRQGSGGSAGDVVARFRLVDVQQRLEAP
PWCQGRQRALDVDTHVTGRDRQVDRVREGKSGVEAVVYQQPPHAPEGDVADELLDVDTPVPEGAALFVRF
GDLGLERHDSFEPGFEVRH
>Thermoplasma-acidophilum DSM 1728, gi|16081186:173296-174453-citrate synthase 
MPETEEISKGLEDVNIKWTRLTTIDGNKGILRYGGYSVEDIIASGAQDEEIQYLFLYGNLPTEQELRKYK
ETVQKGYKIPDFVINAIRQLPRESDAVAMQMAAVAAMAASETKFKWNKDTDRDVAAEMIGRMSAITVNVY
RHIMNMPAELPKPSDSYAESFLNAAFGRKATKEEIDAMNTALILYTDHEVPASTTAGLVAVSTLSDMYSG
ITAALAALKGPLHGGAAEAAIAQFDEIKDPAMVEKWFNDNIINGKKRLMGFGHRVYKTYDPRAKIFKGIA
EKLSSKKPEVHKVYEIATKLEDFGIKAFGSKGIYPNTDYFSGIVYMSIGFPLRNNIYTALFALSRVTGWQ
AHFIEYVEEQQRLIRPRAVYVGPAERKYVPIAERK*
>Thermoplasma-volcanium GSS1, gi|13540831:251796-252956-citrate synthase 
MPETTEEISKGLEDVNIKWTRLTTIDGNKGILRYGGYSVEDIINNGAQAEEIQYLFLYGELPNAQELKIF
KENVQKGYNIPDFVINSIRQLPRESDAVAMQMAAVASMAASEIKFKWNKDTDRDVAAQMIGSMSAITANV
YRHILGMPAERPKPSDSYAESFLKAAFGRNVTKEEVDAINTALILYTDHEVPASTTAGLVAVSTLSDIYS
GITAALAALKGPLHGGAAEAAIAQFDEIKEPSNVEKWFNDNIINGKKRLMGFGHRVYKTYDPRAKIFKGI
AENLSKNNAEVKKIYDIATKLEDLGVKQFGSKGIYPNTDYFSGIVYMSVGFPLRNNIYTALFALSRVTGW
EAHFIEYVEEQQRLIRPRAVYVGPAERKFVKLPDRK*
>Thermus thermophilus HB27, gi|46198308:961812-962945-citrate synthase
LLPGLEGDVGHVQLPDVLGPGAEEAVVQLLVLQDVPHPARDPGHGEDGGEELQAEAQVGVDHPGVEVHVG
VDAPGVQDLPRLLLHDLQDLVLLGVAVLLRHQPGELFQDPGPGVKGLVDPVAHAHDALLLGQLLPHPLPG
PLGGADLLDHAHHGLVGPAVARPLQGGHGGGDGRVEVGLRGEGGDGGEGAGVEAVLGVEDEGRVHEAGLL
GGGLHPVRHVEEVGGVGEVLPGRDGLLALLEALVGGHDGGELGDEVKPLLVEGLPGDVPLGGVQHPELGD
RRAQEAHGVGGDGVALEGLQKVGGQGAAPGEGGRELLQLLPSRQSPVEEEEGGFLKAALLRQLLDGDAVV
VELPLLAVNVAHPAFREENAFQTACHFH