Yersinia pseudotuberculosis

Vibrio parahaemolyticus, a gram-negative marine and ubiquitous, bacterium, is a worldwide cause of food-borne gastroenteritis.YPT can be classified into 14 distinct biotypes,five of which are almost exclusively pathogenic (O1 O5).It is a major cause of food poisoning in Asian -India countries Vibrio parahaemolyticus, an important human pathogen, is associated with gastroenteritis and transmitted through partially cooked seafood. It has become a major concern in the production and trade of marine food products that causes disease.

Organism Details:
Shape and Size
,0.5-0.8 µm by 1-3 µm, Rod-shaped
Genome Information
Yersinia pseudotuberculosis genome (GI:51594359) has circular DNA chromosome of 4744671 bp . It has 4,094 genes and 3,899 coding proteins, Pseudo Genes: 73, rRNAs: 22 ( 5S, 16S, 23S ),,tRNAs: 85. The GC content of Y. enterocolitica is about 47.6% .
Food Source
Pathological Factor
Yersinia pseudotuberculosis produce the cytotoxic necrotizing factor (CNFY), but the functional consequences of this toxin for host-pathogen interactions during the infection are unknown. CNFY has a strong influence on virulence. CNFY toxin is thermo-regulated and highly expressed in all colonized lymphatic tissues and organs. Enteropathogenic yersiniae have been also shown to secrete exotoxins and superantigenic toxin YPM (YPT-derived mitogen) encoded by the ypm gene these toxification leads to causes varing disease.
Disease
Y.pseudotuberculosis(YPT) infections typically present as abscess-forming mesenteric lymphadenitis and diarrhea but can also lead cause secondary complications,such as perforation], subacute obstruction syndrome, intussusceptions and acute renal failure in rare cases. Additionally, patients with YPT colitis severe gastrointestinal bleeding have also been reported. Similar to YE,YPT infections can be mistaken for appendicitis. YPT infections can be acute or chronic, with reticulogranulocytic infiltration,enlarged follicles, and necrosis with abscess formation in mesenteric lymph nodes. Infection is usually self-limiting, but rare cases of sepsis can lead to a very high mortality rate (>75%).. In addition to appendicitis,YPT infections have been confused with tumoral lesions, terminal ileitis, and Crohn s disease. YPT has also been implicated in reactive arthritis, erythema nodosum, and Kwasaki autoimmune syndrome.which lead to cause: Ileocolitis Mesenteric lymphadenitis
Affected Body Organs
Classification
Kingdom Bacteria
Phylum Proteobacteria
Class Gammaproteobacteria
Order Enterobacteriales
Family Enterobacteriaceae
Genus Yersinia
Species Y. pseudotuberculosis