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Hepatitis A virus |
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Organism Details:
Shape and Size
27-32 nm,spherical,
Genome Information
Hepatitis A virus is a positive-strand viruses ( GI:-9626732) has a 7478 bp single stranded linear RNA.The genome structure consists of 3 genes and 1 proteins, and has other 1 RNA The GC content of Hepatitis A virus is about 37.9 %.
Food Source
frozen berries,fish and seafood products (crustaceans, shellfish, molluscs,sandwiches, vegetables, juices, semi-dried tomatoes,Meat and Meat Products
Fish and Fish Products
Water and Beverages bakery products Milk and Milk Products
Soft Cheeses
Fish and Fish Products
Fruits and Vegetables
Water and Beverages
Delicatessen
Pathological Factor
Usaually infected by direct ingestion of contaminated food.After ingestion and uptake from the gastrointestinal tract, the virus replicates in the liver and is excreted into the bile. Cellular immune responses to the virus lead to destruction of infected hepatocytes with consequent development of symptoms and signs of disease.virus, developed an illness with the characteristics of a sporadic case of epidemic jaundice.
Disease
The most characteristic symptom of hepatitis A is jaundice, but milder symptoms of nausea and general malaise without jaundice are common. Patients may feel unwell for several weeks, but recovery is complete. Deaths are rare. Some infections, particularly in children, may be asymptomatic. Like viral gastroenteritis, transmission is by the faecal-oral route, but the primary
site of viral replication is the liver. Virus excretion may commence up to a week before symptoms are apparent, making control difficult.
Affected Body Organs
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