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Section - 1

Databases and tools in Systems biology

String

1. STRING is a database of known and predicted protein-protein interactions.
   
2. The interactions include direct (physical) and indirect (functional) associations; they stem from computational prediction, from knowledge transfer between organisms, and from interactions aggregated from other (primary) databases.
3. https://string-db.org

GeneCards

1. GeneCards is a searchable, integrative database that provides comprehensive, user-friendly information on all annotated and predicted human genes.
   
2. Automatically integrates gene-centric data from ~125 web sources, including genomic, transcriptomic, proteomic, genetic, clinical and functional information aggregated from other (primary) databases.
3. https://www.genecards.org/

GeneMania

1. Genemania helps to predict function of gene or gene set
   
2. 2277 gene networks are present.
3. https://genemania.org/

IntAct

1. IntAct provides a freely available, open source database system and analysis tools for molecular interaction data.
   
2. It is a molecular interaction database derived from literature sources.
3. https://www.ebi.ac.uk/intact/

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